c-kit–Positive Cardiac Progenitor Cells

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c-kit-Positive cardiac progenitor cells: the heart of stemness.

CIRCULATION RESEARCH (ISSN 0009-7330) is published semimonthly except one issue per month in November and December and three issues per month in March and August by Lippincott Williams & Wilkins, at 12107 Insurance Way, Hagerstown, MD 21740. Business offices are located at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103. Production offices are located at 351 West Camden Street, ...

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The very interesting paper by Tallini et al. (1) confirms our suggestion [derived from the study (2) of cardiospheres’ formation by cardiovascular precursors (CPs) isolated from the heart of embryonic, fetal, neonatal, and adult transgenic mice expressing GFP under the control of the c-kit promoter] that c-kit expression identifies in the heart CPs, differentiating into endothelial, cardiac, an...

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In the last few years we have witnessed one of most extraordinary revolutions in cardiovascular medicine, namely, an explosion of basic and clinical studies that support the notion that the diseased heart can be repaired by administration of stem cells, resulting in formation of functional new myocytes and vessels. Although the mechanism by which cell therapy improves cardiac function and anato...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 2013

ISSN: 0009-7330,1524-4571

DOI: 10.1161/circresaha.113.301317